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    MITOCHONDRIAL26 May 2026·9 min read

    MOTS-C: The Complete UAE Research Reference

    A mitochondrial-derived peptide encoded in the 12S rRNA region: discovery, AMPK mechanism, and exercise-mimetic research.

    Overview

    MOTS-C (mitochondrial open-reading-frame of the 12S rRNA type-c) is a mitochondrial-derived peptide of significant interest in metabolic and longevity research. Body Labs supplies it for laboratory use only.

    Mechanism of Action

    Research literature describes MOTS-C as an exercise-mimetic that activates the AMPK pathway and influences metabolic homeostasis, translocating to the nucleus under metabolic stress to regulate adaptive gene expression.

    Research Applications

    Studied areas include insulin-sensitivity research, metabolic regulation, mitochondrial function, and exercise-physiology models. All applications are pre-clinical.

    Pen Format, Handling and CoA

    Supplied as a 32mg pre-filled research pen. Store at 2 to 8C, away from light, and do not freeze. Each batch carries an in-house HPLC Certificate of Analysis, batch-traceable by report number.

    RESEARCH REFERENCES
    Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis. Cell Metab 2015.Reynolds JC, et al. MOTS-c is an exercise-induced mitochondrial-encoded regulator. Nat Commun 2021.
    MOTS-C 32 Pen
    RESEARCH PEN · ≥99% PURITY
    MOTS-C 32 Pen
    HPLC-verified. COA with every batch. Same-day UAE delivery.
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    This guide is provided for scientific reference only. All products are strictly for laboratory research use. Must be 18+ to order.